Description

This track represents the first epigenome map of human fetal and iPSC-derived retinal pigment epithelium (RPE). This hub includes four super tracks:

Display Conventions and Configuration

iPSC-RPE and fetal RPE tracks are displayed using the following colors:

Methods

iPSC lines were reprogrammed as part of the iPSCORE resource.

Credits

Data were generated and processed at the Frazer lab at UC San Diego. For inquiries, please contact us at the following address: madantonio@ucsd.edu

References

Panopoulos AD, D'Antonio M, Benaglio P, Frazer KA et al. iPSCORE: A Resource of 222 iPSC Lines Enabling Functional Characterization of Genetic Variation across a Variety of Cell Types. Stem Cell Reports. 2017. PMID: 28410642; PMC: PMC5390244

DeBoever C, Li H, Jakubosky D, Frazer KA et al. Large-Scale Profiling Reveals the Influence of Genetic Variation on Gene Expression in Human Induced Pluripotent Stem Cells Resource Large-Scale Profiling Reveals the Influence of Genetic Variation on Gene Expression in Human Induced Pluripotent Stem Cell. CEll Stem Cell. 2017. PMID: 28388430; PMC: PMC5444918

Maruotti J, Sripathi SR, Bharti K, Fuller J et al. Small-molecule-directed, efficient generation of retinal pigment epithelium from human pluripotent stem cells. CEll Stem Cell. 2017. PMID: 26269569; PMC: PMC4568212